INSULIN aka Humulin R, Humulin N NPH

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Insulin

To the average person, insulin is best known as the hormone that is deficient in people with diabetes, and it certainly was this relationship that spurred on the study of this fascinating hormone. We are just now realizing that insulin is involved in many cellular processes and in many different ways from what was previously thought.

Insulin is a peptide hormone secreted from the pancreas. In its active form, it is a 51-amino-acid peptide with two different chains, the A chain and the B chain, held together by disulfide bonds. Insulin was one of the first proteins to be cloned and expresses for human need.

Athletes must be able to control their diets for maximum performance. Insulin plays a large role in the choice of a pre-race breakfast for aerobic athletes. If an athlete eats a large, carbohydrate-filled breakfast in the morning, there is a rise in blood glucose, followed by a rise in insulin. This often leads to a fall in blood glucose below the baseline level. It may take hours for the blood glucose levels to come back up. In addition, the high insulin level would cause activation of fat and clycogen synthesis and would inhibit glycogen breakdown. Thus, for a period of time after the high-carbohydrate breakfast, the athlete would be essentially running on empty. For this reason, many runners do not eat before a morning event, or, if they do, they eat little and avoid large amounts of high-glycemic-index foods. Athletes often drink coffee or tea in the morning. Besides the general stimulation of the central nervous system, caffeine also inhibits insulin production and stimulates fat mobilization.

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